• Revision ID 53534 REVISION
  • 2018-03-05 21:22:04
  • by George Engels (talk | contribs)
  • Note: updated with S Abbott's edits
  • Revision ID 54438 REVISION
  • 2018-03-09 20:30:17
  • by Sebastian Abbott (talk | contribs)
  • Note: Further clarification and statements
 
   
Title Title
Diabetes is five different diseases, says new research Diabetes is five different diseases, says new research
Summary Summary
Experts say the discovery marks a new step forward in diabetes treatment but that changing practices won't be immediate Experts say the discovery marks a new step forward in diabetes treatment but that changing practices won't be immediate
Highlights Highlights
Content Content
<strong><a href="http://www.bbc.co.uk/news/health-43246261">Diabetes consists of five separate diseases</a>, say scientists, and the <a href="http://www.thelancet.com/journals/landia/article/PIIS2213-8587(18)30051-2/fulltext?elsca1=tlprts">discovery</a> could bring a new age of targeted and personalized treatment for a condition affecting <a href="http://www.who.int/mediacentre/factsheets/fs312/en/">nearly one in 11 adults</a> worldwide.</strong> <strong><a href="http://www.bbc.co.uk/news/health-43246261">Diabetes consists of five separate diseases</a>, say scientists, and the <a href="http://www.thelancet.com/journals/landia/article/PIIS2213-8587(18)30051-2/fulltext?elsca1=tlprts">discovery</a> could bring a new age of targeted and personalized treatment for a condition affecting <a href="http://www.who.int/mediacentre/factsheets/fs312/en/">nearly one in 11 adults</a> worldwide.</strong>
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Finnish and Swedish researchers have discovered that sufferers of diabetes can be classified into five groups, depending on their diabetic symptoms and the complications that arise from them. <a href="https://en.wikipedia.org/wiki/Diabetes_mellitus">Diabetes</a> – a group of metabolic imbalances that can be characterized by high blood sugar levels over a prolonged period of time – is usually split into Types 1 and 2. Finnish and Swedish researchers have discovered that sufferers of diabetes can be classified into five groups, depending on their diabetic symptoms and the complications that arise from them. <a href="https://en.wikipedia.org/wiki/Diabetes_mellitus">Diabetes</a> – a group of metabolic imbalances that can be characterized by high blood sugar levels over a prolonged period of time – is usually split into Types 1 and 2.
The report indicates that whereas Type 1 diabetes is clearly associated with auto-immune deficiencies, Type 2 appears to be "highly heterogeneous," leading the researchers to identify four new subtypes.  The report suggests that whereas Type 1 diabetes is clearly associated with auto-immune deficiencies, Type 2 appears to be "highly heterogeneous," leading the researchers to identify four new subtypes, each with statistically clear distinguishing features in symptoms and complications, ranging from kidney to retinal problems.
"This new substratification might eventually help to tailor and target early treatment to patients who would benefit most, thereby representing a first step towards precision medicine in diabetes," said the report. "This new substratification might eventually help to tailor and target early treatment to patients who would benefit most, thereby representing a first step towards precision medicine in diabetes," said the report.
Dr. Victoria Salem <a href="http://www.bbc.co.uk/news/health-43246261">told the BBC</a> that the study was a step forward for diabetes treatment but that it wouldn't lead to a change in practice just yet. Dr. Salem is a consultant and clinical scientist at Imperial College London. Dr. Victoria Salem <a href="http://www.bbc.co.uk/news/health-43246261">told the BBC</a> that the study was a step forward for diabetes treatment but that it wouldn't lead to a change in practice just yet. Dr. Salem is a consultant and clinical scientist at Imperial College London.
  The study was based on data from 14,775 Scandinavians; the authors make clear in their paper that the applicability of these subtypes to other ethnic groups requires further investigation.
Whilst the risk of diabetes varies significantly in people around the world, this study was based on data from 14,775 Scandinavians. The study was conducted by Lund University Diabetes Centre in Sweden and Finland's Institute for Molecular Medicine. The report has been published in <a href="http://www.thelancet.com/journals/landia/article/PIIS2213-8587(18)30051-2/fulltext?elsca1=tlpr"><em>The Lancet Diabetes and Endocrinology</em></a> (<em>paid content</em>).  Equally, whilst the researchers acknowledge that this may not yet be the optimum level of classification, it does already appear to be superior to the classic binary Type 1 vs. Type 2 distinction. A web-based tool for assigning patients to one of these subgroups is under development. The study was conducted by Lund University Diabetes Centre in Sweden and Finland's Institute for Molecular Medicine. The report has been published in <a href="http://www.thelancet.com/journals/landia/article/PIIS2213-8587(18)30051-2/fulltext?elsca1=tlpr"><em>The Lancet Diabetes and Endocrinology</em></a> (<em>paid content</em>).
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Categories Categories
Asia, Current Affairs, Finland, Health, Medicine, Pharmaceuticals, Science, Sweden, Technology, Health Asia, Current Affairs, Finland, Health, Medicine, Pharmaceuticals, Science, Sweden, Technology, Health
Article type Article type
emerging emerging
Tags Tags
Diabetes, Finland, Health, Institute for Molecular Medicine Finland, lancet, Lund University Diabetes Centre, medicine, new treatment for diabetes, research, Science, Sweden Diabetes, Finland, Health, Institute for Molecular Medicine Finland, lancet, Lund University Diabetes Centre, medicine, new treatment for diabetes, research, Science, Sweden
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https://s3-eu-west-1.amazonaws.com/wikitribune-uploads-master/2018/03/diabetes.jpg https://s3-eu-west-1.amazonaws.com/wikitribune-uploads-master/2018/03/diabetes.jpg
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